Great city, but a bit sketchy
I'd been to NOLA many times when I was younger, but I guess I'd never realized just how sketchy it is. I'm glad I brought a male friend with me when I went. If you're uncomfortable with sexual things, this is not the city for you! However, the French Quarter is a ton of fun; bring cash to tip the entertainers who are everywhere. It's an expensive town; be prepared to drop a bunch of money. There's a convenient trolley; I'd recommend it rather than paying for parking.
Insider Tip:You've got to know where to go before you go out for the night. You really aren't going to just wander into something good.
Make sure you hit Cafe Du Monde for beignets and BRING CASH (they don't accept other forms of payment in the restaurant).
One bartender at Voodoo BBQ and Grill prides herself on having the best deals in New Orleans: $1 choose your own shots and $2 beers.
PS. When the guy says to you "I'll bet you $5 I know where you got your shoes," the answer is "On your feet on Bourbon St."