All Day Partying
I would suggest not necessarily spending all your time on Bourbon street; it's always crowded, smells bad, and doesn't have any attractions except for bars, really. The trolleys are pretty awesome and there's a lot of great history to the city if you have the time to check out more than just the French Quarter. Best tourist area would have to be the French Market... there were tons of local shops and some great places to eat. Plus it's just by the water.
Insider Tip:Take a short trip to the end of the French Quarter to visit the Allways Lounge. There are some great cabaret shows and it's only a 15 minute walk from the rest of the high spots in the French Quarter.