Great city to visit!
Would highly recommend spending some time in Prague to anyone planning any trip that passes through to near to the Czech Republic. It's a lively city (if that's your thing) but also full of interesting sights and things to do/see during the day. Some of the more tourist-y things maybe aren't worth the wait (e.g. standing in a massive crowd to see the astronomical clock chime on the hour) but it's a great city.
Insider Tip:The Use-It maps movement has an office in Prague (near the 'dancing building,' in summer 2014 anyway) so for a great map, advice on things to do in Prague and other cities across Europe and of course a chat and free tea/coffee, pop by to see them and get a ton of great travel info and advice!