Excellent location. Grote Markt is 15 min walk distance. Ive stayed in the 14 mixed dorm and even that room was really clean.
You only need to take tram(2 or 5) from centraal station. Location is better than Flying Pig Downtown. Uptown's location looks safer. Right behind the Hostel's street there are lots of luxury shopping stores. Very very close to Van Gogh Museum, Iamsterdam letters and Hard Rock cafe.